Niacinamide is the biologically active form of vitamin B-3. It regulates the melanogenesis, suppresses the transfer of melanosomes from melanocytes to keratinocytes. In addition, niacinamide is also a tyrosinase inhibitor. It also promotes acne reduction, increases skin moisture, improves the appearance of aged, hyperpigmented and photodamaged skin. Research shows that it has potential to reduce appearance of wrinkles and fine lines by stimulating collagen & ceramide synthesis, and has soothing activity. Can improve functional & structural integrity of the skin barrier. Combined with vitamin A palmitate shows enhanced skin lightening properties. Niacinamide with retinyl palmitate has been shown to improve hyperpigmentation and increase skin lightening after 4 weeks of treatment compared with vehicle alone.
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